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Prepulsid Brand names, Prepulsid Analogs

Prepulsid Brand Names Mixture

  • No information avaliable

Prepulsid Chemical_Formula


Prepulsid RX_link

Prepulsid fda sheet

Prepulsid msds (material safety sheet)

Prepulsid MSDS

Prepulsid Synthesis Reference

No information avaliable

Prepulsid Molecular Weight

465.945 g/mol

Prepulsid Melting Point

110 oC

Prepulsid H2O Solubility

2.71 mg/L

Prepulsid State


Prepulsid LogP


Prepulsid Dosage Forms

Suspension; Tablet

Prepulsid Indication

For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.

Prepulsid Pharmacology

Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.

Prepulsid Absorption

Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.

Prepulsid side effects and Toxicity

No information avaliable

Prepulsid Patient Information

No information avaliable

Prepulsid Organisms Affected

Humans and other mammals