Cipril
Cipril Brand names, Cipril Analogs
Cipril Brand Names Mixture
- No information avaliable
Cipril Chemical_Formula
C23H29ClFN3O4
Cipril RX_link
http://www.rxlist.com/cgi/generic/cisap.htm
Cipril fda sheet
Cipril msds (material safety sheet)
Cipril Synthesis Reference
No information avaliable
Cipril Molecular Weight
465.945 g/mol
Cipril Melting Point
110 oC
Cipril H2O Solubility
2.71 mg/L
Cipril State
Solid
Cipril LogP
3.802
Cipril Dosage Forms
Suspension; Tablet
Cipril Indication
For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
Cipril Pharmacology
Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.
Cipril Absorption
Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.
Cipril side effects and Toxicity
No information avaliable
Cipril Patient Information
No information avaliable
Cipril Organisms Affected
Humans and other mammals
