Alimix
Alimix Brand names, Alimix Analogs
Alimix Brand Names Mixture
- No information avaliable
Alimix Chemical_Formula
C23H29ClFN3O4
Alimix RX_link
http://www.rxlist.com/cgi/generic/cisap.htm
Alimix fda sheet
Alimix msds (material safety sheet)
Alimix Synthesis Reference
No information avaliable
Alimix Molecular Weight
465.945 g/mol
Alimix Melting Point
110 oC
Alimix H2O Solubility
2.71 mg/L
Alimix State
Solid
Alimix LogP
3.802
Alimix Dosage Forms
Suspension; Tablet
Alimix Indication
For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
Alimix Pharmacology
Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.
Alimix Absorption
Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.
Alimix side effects and Toxicity
No information avaliable
Alimix Patient Information
No information avaliable
Alimix Organisms Affected
Humans and other mammals
