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Propulsid Brand names, Propulsid Analogs

Propulsid Brand Names Mixture

  • No information avaliable

Propulsid Chemical_Formula


Propulsid RX_link

Propulsid fda sheet

Propulsid msds (material safety sheet)

Propulsid MSDS

Propulsid Synthesis Reference

No information avaliable

Propulsid Molecular Weight

465.945 g/mol

Propulsid Melting Point

110 oC

Propulsid H2O Solubility

2.71 mg/L

Propulsid State


Propulsid LogP


Propulsid Dosage Forms

Suspension; Tablet

Propulsid Indication

For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.

Propulsid Pharmacology

Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.

Propulsid Absorption

Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.

Propulsid side effects and Toxicity

No information avaliable

Propulsid Patient Information

No information avaliable

Propulsid Organisms Affected

Humans and other mammals