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Phytomenadione Brand names, Phytomenadione Analogs

Phytomenadione Brand Names Mixture

  • No information avaliable

Phytomenadione Chemical_Formula


Phytomenadione RX_link

Phytomenadione fda sheet

Phytomenadione msds (material safety sheet)

Phytomenadione Synthesis Reference

No information avaliable

Phytomenadione Molecular Weight

450.696 g/mol

Phytomenadione Melting Point

-20 oC

Phytomenadione H2O Solubility

Insoluble in water

Phytomenadione State


Phytomenadione LogP


Phytomenadione Dosage Forms


Phytomenadione Indication

For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia

Phytomenadione Pharmacology

Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

Phytomenadione Absorption

Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.

Phytomenadione side effects and Toxicity

No information avaliable

Phytomenadione Patient Information

No information avaliable

Phytomenadione Organisms Affected

Humans and other mammals