Combinal K1 en es it fr

Combinal K1 Brand names, Combinal K1 Analogs

Combinal K1 Brand Names Mixture

  • No information avaliable

Combinal K1 Chemical_Formula


Combinal K1 RX_link

Combinal K1 fda sheet

Combinal K1 msds (material safety sheet)

Combinal K1 Synthesis Reference

No information avaliable

Combinal K1 Molecular Weight

450.696 g/mol

Combinal K1 Melting Point

-20 oC

Combinal K1 H2O Solubility

Insoluble in water

Combinal K1 State


Combinal K1 LogP


Combinal K1 Dosage Forms


Combinal K1 Indication

For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia

Combinal K1 Pharmacology

Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

Combinal K1 Absorption

Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.

Combinal K1 side effects and Toxicity

No information avaliable

Combinal K1 Patient Information

No information avaliable

Combinal K1 Organisms Affected

Humans and other mammals