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Phylloquinone Brand names, Phylloquinone Analogs

Phylloquinone Brand Names Mixture

  • No information avaliable

Phylloquinone Chemical_Formula


Phylloquinone RX_link

Phylloquinone fda sheet

Phylloquinone msds (material safety sheet)

Phylloquinone Synthesis Reference

No information avaliable

Phylloquinone Molecular Weight

450.696 g/mol

Phylloquinone Melting Point

-20 oC

Phylloquinone H2O Solubility

Insoluble in water

Phylloquinone State


Phylloquinone LogP


Phylloquinone Dosage Forms


Phylloquinone Indication

For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia

Phylloquinone Pharmacology

Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

Phylloquinone Absorption

Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.

Phylloquinone side effects and Toxicity

No information avaliable

Phylloquinone Patient Information

No information avaliable

Phylloquinone Organisms Affected

Humans and other mammals