M.V.I. Pediatric
Brand names,
M.V.I. Pediatric
Analogs
M.V.I. Pediatric
Brand Names Mixture
M.V.I. Pediatric
Chemical_Formula
C31H46O2
M.V.I. Pediatric
RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
M.V.I. Pediatric
fda sheet
M.V.I. Pediatric
msds (material safety sheet)
M.V.I. Pediatric
Synthesis Reference
No information avaliable
M.V.I. Pediatric
Molecular Weight
450.696 g/mol
M.V.I. Pediatric
Melting Point
-20 oC
M.V.I. Pediatric
H2O Solubility
Insoluble in water
M.V.I. Pediatric
State
Liquid
M.V.I. Pediatric
LogP
8.841
M.V.I. Pediatric
Dosage Forms
Liquid
M.V.I. Pediatric
Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
M.V.I. Pediatric
Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
M.V.I. Pediatric
Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
M.V.I. Pediatric
side effects and Toxicity
No information avaliable
M.V.I. Pediatric
Patient Information
No information avaliable
M.V.I. Pediatric
Organisms Affected
Humans and other mammals