2-Methyl-3-phythyl-1,4-naphthochinon
Brand names,
2-Methyl-3-phythyl-1,4-naphthochinon
Analogs
2-Methyl-3-phythyl-1,4-naphthochinon
Brand Names Mixture
2-Methyl-3-phythyl-1,4-naphthochinon
Chemical_Formula
C31H46O2
2-Methyl-3-phythyl-1,4-naphthochinon
RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
2-Methyl-3-phythyl-1,4-naphthochinon
fda sheet
2-Methyl-3-phythyl-1,4-naphthochinon
msds (material safety sheet)
2-Methyl-3-phythyl-1,4-naphthochinon
Synthesis Reference
No information avaliable
2-Methyl-3-phythyl-1,4-naphthochinon
Molecular Weight
450.696 g/mol
2-Methyl-3-phythyl-1,4-naphthochinon
Melting Point
-20 oC
2-Methyl-3-phythyl-1,4-naphthochinon
H2O Solubility
Insoluble in water
2-Methyl-3-phythyl-1,4-naphthochinon
State
Liquid
2-Methyl-3-phythyl-1,4-naphthochinon
LogP
8.841
2-Methyl-3-phythyl-1,4-naphthochinon
Dosage Forms
Liquid
2-Methyl-3-phythyl-1,4-naphthochinon
Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
2-Methyl-3-phythyl-1,4-naphthochinon
Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
2-Methyl-3-phythyl-1,4-naphthochinon
Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
2-Methyl-3-phythyl-1,4-naphthochinon
side effects and Toxicity
No information avaliable
2-Methyl-3-phythyl-1,4-naphthochinon
Patient Information
No information avaliable
2-Methyl-3-phythyl-1,4-naphthochinon
Organisms Affected
Humans and other mammals