PharmacyCodes



Mephyton (TN) en es it fr

Mephyton (TN) Brand names, Mephyton (TN) Analogs

Mephyton (TN) Brand Names Mixture

  • No information avaliable

Mephyton (TN) Chemical_Formula

C31H46O2

Mephyton (TN) RX_link

http://www.rxlist.com/cgi/generic3/phytonadione.htm

Mephyton (TN) fda sheet

Mephyton (TN) msds (material safety sheet)

Mephyton (TN) Synthesis Reference

No information avaliable

Mephyton (TN) Molecular Weight

450.696 g/mol

Mephyton (TN) Melting Point

-20 oC

Mephyton (TN) H2O Solubility

Insoluble in water

Mephyton (TN) State

Liquid

Mephyton (TN) LogP

8.841

Mephyton (TN) Dosage Forms

Liquid

Mephyton (TN) Indication

For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia

Mephyton (TN) Pharmacology

Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

Mephyton (TN) Absorption

Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.

Mephyton (TN) side effects and Toxicity

No information avaliable

Mephyton (TN) Patient Information

No information avaliable

Mephyton (TN) Organisms Affected

Humans and other mammals