α-Phylloquinone
α-Phylloquinone Brand names, α-Phylloquinone Analogs
- α-Phylloquinone
- 1,4-Naphthoquinone, 2-methyl-3-phytyl-
- 2', 3'-trans-Vitamin K1
- 2-Methyl-3-phythyl-1,4-naphthochinon
- 3-Phytylmenadione
- Antihemorrhagic vitamin
- Aqua-Mephytin
- AquaMEPHYTON
- Combinal K1
- K-Ject
- Kativ N
- Kephton
- Kinadion
- Konakion
- M.V.I. Pediatric
- Menadione
- Mephyton
- Mephyton (TN)
- Mono-Kay
- Monodion
- Phyllochinon
- Phylloquinone
- Phythyl-menadion
- Phythyl-menadion (GERMAN)
- Phytomenadione
- Phytonadione (JP14/USP)
- Phytylmenadione
- Synthex P
- VITAMIN K1
- Vitamin K
- Vitamin K1 (VAN)
- Vitaped
α-Phylloquinone Brand Names Mixture
- No information avaliable
α-Phylloquinone Chemical_Formula
C31H46O2
α-Phylloquinone RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
α-Phylloquinone fda sheet
α-Phylloquinone msds (material safety sheet)
α-Phylloquinone Synthesis Reference
No information avaliable
α-Phylloquinone Molecular Weight
450.696 g/mol
α-Phylloquinone Melting Point
-20 oC
α-Phylloquinone H2O Solubility
Insoluble in water
α-Phylloquinone State
Liquid
α-Phylloquinone LogP
8.841
α-Phylloquinone Dosage Forms
Liquid
α-Phylloquinone Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
α-Phylloquinone Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
α-Phylloquinone Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
α-Phylloquinone side effects and Toxicity
No information avaliable
α-Phylloquinone Patient Information
No information avaliable
α-Phylloquinone Organisms Affected
Humans and other mammals
