Phenylethylmethylhydantoin en es it fr

Phenylethylmethylhydantoin Brand names, Phenylethylmethylhydantoin Analogs

Phenylethylmethylhydantoin Brand Names Mixture

  • No information avaliable

Phenylethylmethylhydantoin Chemical_Formula

C12H14N2O2

Phenylethylmethylhydantoin RX_link

No information avaliable

Phenylethylmethylhydantoin fda sheet

Phenylethylmethylhydantoin msds (material safety sheet)

Phenylethylmethylhydantoin Synthesis Reference

No information avaliable

Phenylethylmethylhydantoin Molecular Weight

218.252 g/mol

Phenylethylmethylhydantoin Melting Point

135 oC

Phenylethylmethylhydantoin H2O Solubility

1270 mg/L

Phenylethylmethylhydantoin State

Solid

Phenylethylmethylhydantoin LogP

1.515

Phenylethylmethylhydantoin Dosage Forms

Tablet

Phenylethylmethylhydantoin Indication

For the treatment of refractory partial epilepsy.

Phenylethylmethylhydantoin Pharmacology

Mephenytoin is an antiepileptic drug which can be useful in the treatment of epilepsy. The primary site of action appears to be the motor cortex where spread of seizure activity is inhibited. Possibly by promoting sodium efflux from neurons, mephenytoin tends to stabilize the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing membrane sodium gradient. This includes the reduction of posttetanic potentiation at synapses. Loss of posttetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas. Mephenytoin reduces the maximal activity of brain stem centers responsible for the tonic phase of tonic-clonic (grand mal) seizures.

Phenylethylmethylhydantoin Absorption

No information avaliable

Phenylethylmethylhydantoin side effects and Toxicity

No information avaliable

Phenylethylmethylhydantoin Patient Information

Patient Information:

Discuss with your doctor about the risks of taking Mephenytoin. Mephenytoin may
pass into the breast milk. If you are breast feeding or have any other medical condition,
make sure you let the doctor know.
Alcohol and some other medications may affect the effect of Mephenytoin.
Do not change dose and dosing schedule without consulting your doctor.

Phenylethylmethylhydantoin Organisms Affected

Humans and other mammals