PharmacyCodes



Mesontoin en es it fr

Mesontoin Brand names, Mesontoin Analogs

Mesontoin Brand Names Mixture

  • No information avaliable

Mesontoin Chemical_Formula

C12H14N2O2

Mesontoin RX_link

No information avaliable

Mesontoin fda sheet

Mesontoin msds (material safety sheet)

Mesontoin Synthesis Reference

No information avaliable

Mesontoin Molecular Weight

218.252 g/mol

Mesontoin Melting Point

135 oC

Mesontoin H2O Solubility

1270 mg/L

Mesontoin State

Solid

Mesontoin LogP

1.515

Mesontoin Dosage Forms

Tablet

Mesontoin Indication

For the treatment of refractory partial epilepsy.

Mesontoin Pharmacology

Mephenytoin is an antiepileptic drug which can be useful in the treatment of epilepsy. The primary site of action appears to be the motor cortex where spread of seizure activity is inhibited. Possibly by promoting sodium efflux from neurons, mephenytoin tends to stabilize the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing membrane sodium gradient. This includes the reduction of posttetanic potentiation at synapses. Loss of posttetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas. Mephenytoin reduces the maximal activity of brain stem centers responsible for the tonic phase of tonic-clonic (grand mal) seizures.

Mesontoin Absorption

No information avaliable

Mesontoin side effects and Toxicity

No information avaliable

Mesontoin Patient Information

Patient Information:

Discuss with your doctor about the risks of taking Mephenytoin. Mephenytoin may
pass into the breast milk. If you are breast feeding or have any other medical condition,
make sure you let the doctor know.
Alcohol and some other medications may affect the effect of Mephenytoin.
Do not change dose and dosing schedule without consulting your doctor.

Mesontoin Organisms Affected

Humans and other mammals