PharmacyCodes



Phenantoin en es it fr

Phenantoin Brand names, Phenantoin Analogs

Phenantoin Brand Names Mixture

  • No information avaliable

Phenantoin Chemical_Formula

C12H14N2O2

Phenantoin RX_link

No information avaliable

Phenantoin fda sheet

Phenantoin msds (material safety sheet)

Phenantoin Synthesis Reference

No information avaliable

Phenantoin Molecular Weight

218.252 g/mol

Phenantoin Melting Point

135 oC

Phenantoin H2O Solubility

1270 mg/L

Phenantoin State

Solid

Phenantoin LogP

1.515

Phenantoin Dosage Forms

Tablet

Phenantoin Indication

For the treatment of refractory partial epilepsy.

Phenantoin Pharmacology

Mephenytoin is an antiepileptic drug which can be useful in the treatment of epilepsy. The primary site of action appears to be the motor cortex where spread of seizure activity is inhibited. Possibly by promoting sodium efflux from neurons, mephenytoin tends to stabilize the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing membrane sodium gradient. This includes the reduction of posttetanic potentiation at synapses. Loss of posttetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas. Mephenytoin reduces the maximal activity of brain stem centers responsible for the tonic phase of tonic-clonic (grand mal) seizures.

Phenantoin Absorption

No information avaliable

Phenantoin side effects and Toxicity

No information avaliable

Phenantoin Patient Information

Patient Information:

Discuss with your doctor about the risks of taking Mephenytoin. Mephenytoin may
pass into the breast milk. If you are breast feeding or have any other medical condition,
make sure you let the doctor know.
Alcohol and some other medications may affect the effect of Mephenytoin.
Do not change dose and dosing schedule without consulting your doctor.

Phenantoin Organisms Affected

Humans and other mammals