Phenacemide
Brand names,
Phenacemide
Analogs
Phenacemide
Brand Names Mixture
Phenacemide
Chemical_Formula
C9H10N2O2
Phenacemide
RX_link
No information avaliable
Phenacemide
fda sheet
Phenacemide
msds (material safety sheet)
Phenacemide
Synthesis Reference
No information avaliable
Phenacemide
Molecular Weight
178.188 g/mol
Phenacemide
Melting Point
215 oC
Phenacemide
H2O Solubility
10.2 g/L
Phenacemide
State
Solid
Phenacemide
LogP
1.07
Phenacemide
Dosage Forms
Tablet
Phenacemide
Indication
Used to control certain seizures in the treatment of epilepsy.
Phenacemide
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Phenacemide
Absorption
Almost completely absorbed.
Phenacemide
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Phenacemide
Patient Information
No information avaliable
Phenacemide
Organisms Affected
Humans and other mammals