Phenylacetyluree
Brand names,
Phenylacetyluree
Analogs
Phenylacetyluree
Brand Names Mixture
Phenylacetyluree
Chemical_Formula
C9H10N2O2
Phenylacetyluree
RX_link
No information avaliable
Phenylacetyluree
fda sheet
Phenylacetyluree
msds (material safety sheet)
Phenylacetyluree
Synthesis Reference
No information avaliable
Phenylacetyluree
Molecular Weight
178.188 g/mol
Phenylacetyluree
Melting Point
215 oC
Phenylacetyluree
H2O Solubility
10.2 g/L
Phenylacetyluree
State
Solid
Phenylacetyluree
LogP
1.07
Phenylacetyluree
Dosage Forms
Tablet
Phenylacetyluree
Indication
Used to control certain seizures in the treatment of epilepsy.
Phenylacetyluree
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Phenylacetyluree
Absorption
Almost completely absorbed.
Phenylacetyluree
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Phenylacetyluree
Patient Information
No information avaliable
Phenylacetyluree
Organisms Affected
Humans and other mammals