Phenacetylcarbamide
Brand names,
Phenacetylcarbamide
Analogs
Phenacetylcarbamide
Brand Names Mixture
Phenacetylcarbamide
Chemical_Formula
C9H10N2O2
Phenacetylcarbamide
RX_link
No information avaliable
Phenacetylcarbamide
fda sheet
Phenacetylcarbamide
msds (material safety sheet)
Phenacetylcarbamide
Synthesis Reference
No information avaliable
Phenacetylcarbamide
Molecular Weight
178.188 g/mol
Phenacetylcarbamide
Melting Point
215 oC
Phenacetylcarbamide
H2O Solubility
10.2 g/L
Phenacetylcarbamide
State
Solid
Phenacetylcarbamide
LogP
1.07
Phenacetylcarbamide
Dosage Forms
Tablet
Phenacetylcarbamide
Indication
Used to control certain seizures in the treatment of epilepsy.
Phenacetylcarbamide
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Phenacetylcarbamide
Absorption
Almost completely absorbed.
Phenacetylcarbamide
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Phenacetylcarbamide
Patient Information
No information avaliable
Phenacetylcarbamide
Organisms Affected
Humans and other mammals