Epiclase
Brand names,
Epiclase
Analogs
Epiclase
Brand Names Mixture
Epiclase
Chemical_Formula
C9H10N2O2
Epiclase
RX_link
No information avaliable
Epiclase
fda sheet
Epiclase
msds (material safety sheet)
Epiclase
Synthesis Reference
No information avaliable
Epiclase
Molecular Weight
178.188 g/mol
Epiclase
Melting Point
215 oC
Epiclase
H2O Solubility
10.2 g/L
Epiclase
State
Solid
Epiclase
LogP
1.07
Epiclase
Dosage Forms
Tablet
Epiclase
Indication
Used to control certain seizures in the treatment of epilepsy.
Epiclase
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Epiclase
Absorption
Almost completely absorbed.
Epiclase
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Epiclase
Patient Information
No information avaliable
Epiclase
Organisms Affected
Humans and other mammals