Carbamide phenylacetate
Brand names,
Carbamide phenylacetate
Analogs
Carbamide phenylacetate
Brand Names Mixture
Carbamide phenylacetate
Chemical_Formula
C9H10N2O2
Carbamide phenylacetate
RX_link
No information avaliable
Carbamide phenylacetate
fda sheet
Carbamide phenylacetate
msds (material safety sheet)
Carbamide phenylacetate
Synthesis Reference
No information avaliable
Carbamide phenylacetate
Molecular Weight
178.188 g/mol
Carbamide phenylacetate
Melting Point
215 oC
Carbamide phenylacetate
H2O Solubility
10.2 g/L
Carbamide phenylacetate
State
Solid
Carbamide phenylacetate
LogP
1.07
Carbamide phenylacetate
Dosage Forms
Tablet
Carbamide phenylacetate
Indication
Used to control certain seizures in the treatment of epilepsy.
Carbamide phenylacetate
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Carbamide phenylacetate
Absorption
Almost completely absorbed.
Carbamide phenylacetate
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Carbamide phenylacetate
Patient Information
No information avaliable
Carbamide phenylacetate
Organisms Affected
Humans and other mammals