Phenylacetylurea
Brand names,
Phenylacetylurea
Analogs
Phenylacetylurea
Brand Names Mixture
Phenylacetylurea
Chemical_Formula
C9H10N2O2
Phenylacetylurea
RX_link
No information avaliable
Phenylacetylurea
fda sheet
Phenylacetylurea
msds (material safety sheet)
Phenylacetylurea
Synthesis Reference
No information avaliable
Phenylacetylurea
Molecular Weight
178.188 g/mol
Phenylacetylurea
Melting Point
215 oC
Phenylacetylurea
H2O Solubility
10.2 g/L
Phenylacetylurea
State
Solid
Phenylacetylurea
LogP
1.07
Phenylacetylurea
Dosage Forms
Tablet
Phenylacetylurea
Indication
Used to control certain seizures in the treatment of epilepsy.
Phenylacetylurea
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Phenylacetylurea
Absorption
Almost completely absorbed.
Phenylacetylurea
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Phenylacetylurea
Patient Information
No information avaliable
Phenylacetylurea
Organisms Affected
Humans and other mammals