PA
PA Brand names, PA Analogs
PA Brand Names Mixture
- No information avaliable
PA Chemical_Formula
C2H5N1O2
PA RX_link
No information avaliable
PA fda sheet
PA msds (material safety sheet)
PA Synthesis Reference
No information avaliable
PA Molecular Weight
75.067 g/mol
PA Melting Point
240 oC
PA H2O Solubility
No information avaliable
PA State
Solid, white powder
PA LogP
-3.415
PA Dosage Forms
Capsules, Irrigation solution, powder and tablets.
PA Indication
Supplemental glycine may have antispastic activity. Very early findings suggest it may also have antipsychotic activity as well as antioxidant and anti-inflammatory activities.
PA Pharmacology
Helps trigger the release of oxygen to the energy requiring cell-making process; Important in the manufacturing of hormones responsible for a strong immune system.
PA Absorption
Absorbed from the small intestine via an active transport mechanism.
PA side effects and Toxicity
ORL-RAT LD50 7930 mg kg-1, SCU-RAT LD50 5200 mg kg-1, IVN-RAT LD50 2600 mg kg-1, ORL-MUS LD50 4920 mg kg-1; Doses of 1 gram daily are very well tolerated. Mild gastrointestinal symptoms are infrequently noted. In one study doses of 90 grams daily were also well tole.
PA Patient Information
Glycine supplementation should be avoided by pregnant women and nursing mothers. Because of some conversion of glycine to ammonia, those with hepatic impairment should avoid glycine supplementation unless prescribed.
PA Organisms Affected
Humans and other mammals
