Efron
Brand names,
Efron
Analogs
Efron
Brand Names Mixture
Efron
Chemical_Formula
C9H10N2O2
Efron
RX_link
No information avaliable
Efron
fda sheet
Efron
msds (material safety sheet)
Efron
Synthesis Reference
No information avaliable
Efron
Molecular Weight
178.188 g/mol
Efron
Melting Point
215 oC
Efron
H2O Solubility
10.2 g/L
Efron
State
Solid
Efron
LogP
1.07
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Dosage Forms
Tablet
Efron
Indication
Used to control certain seizures in the treatment of epilepsy.
Efron
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Efron
Absorption
Almost completely absorbed.
Efron
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Efron
Patient Information
No information avaliable
Efron
Organisms Affected
Humans and other mammals