Comitiadone
Brand names,
Comitiadone
Analogs
Comitiadone
Brand Names Mixture
Comitiadone
Chemical_Formula
C9H10N2O2
Comitiadone
RX_link
No information avaliable
Comitiadone
fda sheet
Comitiadone
msds (material safety sheet)
Comitiadone
Synthesis Reference
No information avaliable
Comitiadone
Molecular Weight
178.188 g/mol
Comitiadone
Melting Point
215 oC
Comitiadone
H2O Solubility
10.2 g/L
Comitiadone
State
Solid
Comitiadone
LogP
1.07
Comitiadone
Dosage Forms
Tablet
Comitiadone
Indication
Used to control certain seizures in the treatment of epilepsy.
Comitiadone
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Comitiadone
Absorption
Almost completely absorbed.
Comitiadone
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Comitiadone
Patient Information
No information avaliable
Comitiadone
Organisms Affected
Humans and other mammals