Phetylureum
Brand names,
Phetylureum
Analogs
Phetylureum
Brand Names Mixture
Phetylureum
Chemical_Formula
C9H10N2O2
Phetylureum
RX_link
No information avaliable
Phetylureum
fda sheet
Phetylureum
msds (material safety sheet)
Phetylureum
Synthesis Reference
No information avaliable
Phetylureum
Molecular Weight
178.188 g/mol
Phetylureum
Melting Point
215 oC
Phetylureum
H2O Solubility
10.2 g/L
Phetylureum
State
Solid
Phetylureum
LogP
1.07
Phetylureum
Dosage Forms
Tablet
Phetylureum
Indication
Used to control certain seizures in the treatment of epilepsy.
Phetylureum
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Phetylureum
Absorption
Almost completely absorbed.
Phetylureum
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Phetylureum
Patient Information
No information avaliable
Phetylureum
Organisms Affected
Humans and other mammals