Acetylureum
Brand names,
Acetylureum
Analogs
Acetylureum
Brand Names Mixture
Acetylureum
Chemical_Formula
C9H10N2O2
Acetylureum
RX_link
No information avaliable
Acetylureum
fda sheet
Acetylureum
msds (material safety sheet)
Acetylureum
Synthesis Reference
No information avaliable
Acetylureum
Molecular Weight
178.188 g/mol
Acetylureum
Melting Point
215 oC
Acetylureum
H2O Solubility
10.2 g/L
Acetylureum
State
Solid
Acetylureum
LogP
1.07
Acetylureum
Dosage Forms
Tablet
Acetylureum
Indication
Used to control certain seizures in the treatment of epilepsy.
Acetylureum
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Acetylureum
Absorption
Almost completely absorbed.
Acetylureum
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Acetylureum
Patient Information
No information avaliable
Acetylureum
Organisms Affected
Humans and other mammals