Phenacetylurea
Brand names,
Phenacetylurea
Analogs
Phenacetylurea
Brand Names Mixture
Phenacetylurea
Chemical_Formula
C9H10N2O2
Phenacetylurea
RX_link
No information avaliable
Phenacetylurea
fda sheet
Phenacetylurea
msds (material safety sheet)
Phenacetylurea
Synthesis Reference
No information avaliable
Phenacetylurea
Molecular Weight
178.188 g/mol
Phenacetylurea
Melting Point
215 oC
Phenacetylurea
H2O Solubility
10.2 g/L
Phenacetylurea
State
Solid
Phenacetylurea
LogP
1.07
Phenacetylurea
Dosage Forms
Tablet
Phenacetylurea
Indication
Used to control certain seizures in the treatment of epilepsy.
Phenacetylurea
Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
Phenacetylurea
Absorption
Almost completely absorbed.
Phenacetylurea
side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Phenacetylurea
Patient Information
No information avaliable
Phenacetylurea
Organisms Affected
Humans and other mammals