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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C9H10N2O2
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
178.188 g/mol
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Melting Point
215 oC
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H2O Solubility
10.2 g/L
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State
Solid
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LogP
1.07
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Dosage Forms
Tablet
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Indication
Used to control certain seizures in the treatment of epilepsy.
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Pharmacology
Phenacemide is a ureal anticonvulsant indicated for control of severe epilepsy, particularly mixed forms of complex partial (psychomotor or temporal lobe) seizures, refractory to other anticonvulsants. Phenacemide elevates the threshold for minimal electroshock convulsions and abolishes the tonic phase of maximal electroshock seizures. It also prevents or modifies seizures induced by pentylenetetrazol or other convulsants.
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Absorption
Almost completely absorbed.
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side effects and Toxicity
Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals