Levocabastine
Brand names,
Levocabastine
Analogs
Levocabastine
Brand Names Mixture
Levocabastine
Chemical_Formula
C26H29FN2O2
Levocabastine
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Levocabastine
fda sheet
Levocabastine
msds (material safety sheet)
Levocabastine
Synthesis Reference
No information avaliable
Levocabastine
Molecular Weight
420.519 g/mol
Levocabastine
Melting Point
No information avaliable
Levocabastine
H2O Solubility
>0.5 mg/mL
Levocabastine
State
Solid
Levocabastine
LogP
6.3
Levocabastine
Dosage Forms
Drops; Spray
Levocabastine
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Levocabastine
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Levocabastine
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Levocabastine
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Levocabastine
Patient Information
Levocabastine
Organisms Affected
Humans and other mammals