Kristalose
Brand names,
Kristalose
Analogs
Kristalose
Brand Names Mixture
Kristalose
Chemical_Formula
C26H29FN2O2
Kristalose
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Kristalose
fda sheet
Kristalose
msds (material safety sheet)
Kristalose
Synthesis Reference
No information avaliable
Kristalose
Molecular Weight
420.519 g/mol
Kristalose
Melting Point
No information avaliable
Kristalose
H2O Solubility
>0.5 mg/mL
Kristalose
State
Solid
Kristalose
LogP
6.3
Kristalose
Dosage Forms
Drops; Spray
Kristalose
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Kristalose
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Kristalose
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Kristalose
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Kristalose
Patient Information
Kristalose
Organisms Affected
Humans and other mammals