Enulose
Brand names,
Enulose
Analogs
Enulose
Brand Names Mixture
Enulose
Chemical_Formula
C26H29FN2O2
Enulose
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Enulose
fda sheet
Enulose
msds (material safety sheet)
Enulose
Synthesis Reference
No information avaliable
Enulose
Molecular Weight
420.519 g/mol
Enulose
Melting Point
No information avaliable
Enulose
H2O Solubility
>0.5 mg/mL
Enulose
State
Solid
Enulose
LogP
6.3
Enulose
Dosage Forms
Drops; Spray
Enulose
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Enulose
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Enulose
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Enulose
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Enulose
Patient Information
Enulose
Organisms Affected
Humans and other mammals