Duphalac
Brand names,
Duphalac
Analogs
Duphalac
Brand Names Mixture
Duphalac
Chemical_Formula
C26H29FN2O2
Duphalac
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Duphalac
fda sheet
Duphalac
msds (material safety sheet)
Duphalac
Synthesis Reference
No information avaliable
Duphalac
Molecular Weight
420.519 g/mol
Duphalac
Melting Point
No information avaliable
Duphalac
H2O Solubility
>0.5 mg/mL
Duphalac
State
Solid
Duphalac
LogP
6.3
Duphalac
Dosage Forms
Drops; Spray
Duphalac
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Duphalac
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Duphalac
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Duphalac
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Duphalac
Patient Information
Duphalac
Organisms Affected
Humans and other mammals