Heptalac
Brand names,
Heptalac
Analogs
Heptalac
Brand Names Mixture
Heptalac
Chemical_Formula
C26H29FN2O2
Heptalac
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Heptalac
fda sheet
Heptalac
msds (material safety sheet)
Heptalac
Synthesis Reference
No information avaliable
Heptalac
Molecular Weight
420.519 g/mol
Heptalac
Melting Point
No information avaliable
Heptalac
H2O Solubility
>0.5 mg/mL
Heptalac
State
Solid
Heptalac
LogP
6.3
Heptalac
Dosage Forms
Drops; Spray
Heptalac
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Heptalac
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Heptalac
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Heptalac
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Heptalac
Patient Information
Heptalac
Organisms Affected
Humans and other mammals