Generlac
Brand names,
Generlac
Analogs
Generlac
Brand Names Mixture
Generlac
Chemical_Formula
C26H29FN2O2
Generlac
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Generlac
fda sheet
Generlac
msds (material safety sheet)
Generlac
Synthesis Reference
No information avaliable
Generlac
Molecular Weight
420.519 g/mol
Generlac
Melting Point
No information avaliable
Generlac
H2O Solubility
>0.5 mg/mL
Generlac
State
Solid
Generlac
LogP
6.3
Generlac
Dosage Forms
Drops; Spray
Generlac
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Generlac
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Generlac
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Generlac
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Generlac
Patient Information
Generlac
Organisms Affected
Humans and other mammals