Laevolac
Brand names,
Laevolac
Analogs
Laevolac
Brand Names Mixture
Laevolac
Chemical_Formula
C26H29FN2O2
Laevolac
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Laevolac
fda sheet
Laevolac
msds (material safety sheet)
Laevolac
Synthesis Reference
No information avaliable
Laevolac
Molecular Weight
420.519 g/mol
Laevolac
Melting Point
No information avaliable
Laevolac
H2O Solubility
>0.5 mg/mL
Laevolac
State
Solid
Laevolac
LogP
6.3
Laevolac
Dosage Forms
Drops; Spray
Laevolac
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Laevolac
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Laevolac
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Laevolac
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Laevolac
Patient Information
Laevolac
Organisms Affected
Humans and other mammals