Cephulac
Brand names,
Cephulac
Analogs
Cephulac
Brand Names Mixture
Cephulac
Chemical_Formula
C26H29FN2O2
Cephulac
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Cephulac
fda sheet
Cephulac
msds (material safety sheet)
Cephulac
Synthesis Reference
No information avaliable
Cephulac
Molecular Weight
420.519 g/mol
Cephulac
Melting Point
No information avaliable
Cephulac
H2O Solubility
>0.5 mg/mL
Cephulac
State
Solid
Cephulac
LogP
6.3
Cephulac
Dosage Forms
Drops; Spray
Cephulac
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Cephulac
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Cephulac
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Cephulac
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Cephulac
Patient Information
Cephulac
Organisms Affected
Humans and other mammals