Isolactose
Brand names,
Isolactose
Analogs
Isolactose
Brand Names Mixture
Isolactose
Chemical_Formula
C26H29FN2O2
Isolactose
RX_link
http://www.rxlist.com/cgi/generic2/livostin.htm
Isolactose
fda sheet
Isolactose
msds (material safety sheet)
Isolactose
Synthesis Reference
No information avaliable
Isolactose
Molecular Weight
420.519 g/mol
Isolactose
Melting Point
No information avaliable
Isolactose
H2O Solubility
>0.5 mg/mL
Isolactose
State
Solid
Isolactose
LogP
6.3
Isolactose
Dosage Forms
Drops; Spray
Isolactose
Indication
As an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
Isolactose
Pharmacology
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators from mast cells and on the chemotaxis of polymorphonuclear leukocytes and eosinophils. Both histamine and antigens induced conjunctivitis can be inhibited by levocabastine. Levocabastine can also reduce symptoms of allergic rhinitis by preventing an increase in vascular permeability of nasal mucosa.
Isolactose
Absorption
After instillation in the eye, levocabastine is systemically absorbed, albeit at low levels.
Isolactose
side effects and Toxicity
Adverse effects include visual disturbances, dry mouth, cough, nausea, eyelid edema and lacrimation.
Isolactose
Patient Information
Isolactose
Organisms Affected
Humans and other mammals