Co-Trimoxazole
Brand names,
Co-Trimoxazole
Analogs
Co-Trimoxazole
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Co-Trimoxazole
Chemical_Formula
C10H11N3O3S
Co-Trimoxazole
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Co-Trimoxazole
fda sheet
Co-Trimoxazole
msds (material safety sheet)
Co-Trimoxazole
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Co-Trimoxazole
Molecular Weight
253.279 g/mol
Co-Trimoxazole
Melting Point
167 oC
Co-Trimoxazole
H2O Solubility
610 mg/L
Co-Trimoxazole
State
Solid
Co-Trimoxazole
LogP
2.447
Co-Trimoxazole
Dosage Forms
Tablet
Co-Trimoxazole
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Co-Trimoxazole
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Co-Trimoxazole
Absorption
Rapidly absorbed following oral administration.
Co-Trimoxazole
side effects and Toxicity
No information avaliable
Co-Trimoxazole
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Co-Trimoxazole
Organisms Affected
Gram negative and gram positive bacteria