Sulfisomezole
Brand names,
Sulfisomezole
Analogs
Sulfisomezole
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Sulfisomezole
Chemical_Formula
C10H11N3O3S
Sulfisomezole
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Sulfisomezole
fda sheet
Sulfisomezole
msds (material safety sheet)
Sulfisomezole
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Sulfisomezole
Molecular Weight
253.279 g/mol
Sulfisomezole
Melting Point
167 oC
Sulfisomezole
H2O Solubility
610 mg/L
Sulfisomezole
State
Solid
Sulfisomezole
LogP
2.447
Sulfisomezole
Dosage Forms
Tablet
Sulfisomezole
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Sulfisomezole
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Sulfisomezole
Absorption
Rapidly absorbed following oral administration.
Sulfisomezole
side effects and Toxicity
No information avaliable
Sulfisomezole
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Sulfisomezole
Organisms Affected
Gram negative and gram positive bacteria