Sulpha-Methoxizole
Brand names,
Sulpha-Methoxizole
Analogs
Sulpha-Methoxizole
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Sulpha-Methoxizole
Chemical_Formula
C10H11N3O3S
Sulpha-Methoxizole
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Sulpha-Methoxizole
fda sheet
Sulpha-Methoxizole
msds (material safety sheet)
Sulpha-Methoxizole
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Sulpha-Methoxizole
Molecular Weight
253.279 g/mol
Sulpha-Methoxizole
Melting Point
167 oC
Sulpha-Methoxizole
H2O Solubility
610 mg/L
Sulpha-Methoxizole
State
Solid
Sulpha-Methoxizole
LogP
2.447
Sulpha-Methoxizole
Dosage Forms
Tablet
Sulpha-Methoxizole
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Sulpha-Methoxizole
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Sulpha-Methoxizole
Absorption
Rapidly absorbed following oral administration.
Sulpha-Methoxizole
side effects and Toxicity
No information avaliable
Sulpha-Methoxizole
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Sulpha-Methoxizole
Organisms Affected
Gram negative and gram positive bacteria