Septran
Brand names,
Septran
Analogs
Septran
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Septran
Chemical_Formula
C10H11N3O3S
Septran
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Septran
fda sheet
Septran
msds (material safety sheet)
Septran
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Septran
Molecular Weight
253.279 g/mol
Septran
Melting Point
167 oC
Septran
H2O Solubility
610 mg/L
Septran
State
Solid
Septran
LogP
2.447
Septran
Dosage Forms
Tablet
Septran
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Septran
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Septran
Absorption
Rapidly absorbed following oral administration.
Septran
side effects and Toxicity
No information avaliable
Septran
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Septran
Organisms Affected
Gram negative and gram positive bacteria