SIM
SIM Brand names, SIM Analogs
- Apo-Sulfamethoxazole
- Azo Gantanol
- Azo-Gantanol
- Bactrimel
- Co-trimoxazole
- Cotrim
- Cotrim D.S.
- Eusaprim
- Fectrim
- Gamazole
- Gantanol
- Gantanol-DS
- Metoxal
- Radonil
- SIM
- Septran
- Septrin
- Simsinomin
- Sinomin
- Sulfamethalazole
- Sulfamethoprim
- Sulfamethoprim-DS
- Sulfamethoxazol
- Sulfamethoxizole
- Sulfamethylisoxazole
- Sulfisomezole
- Sulmeprim
- Sulmeprim Pediatric
- Sulpha-Methoxizole
- Sulphamethalazole
- Sulphamethoxazol
- Sulphamethoxazole
- Sulphamethoxazole BP 98
- Sulphamethylisoxazole
- Sulphisomezole
- Trib
- Urobak
- Uroplus DS
- Uroplus SS
SIM Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
SIM Chemical_Formula
C10H11N3O3S
SIM RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
SIM fda sheet
SIM msds (material safety sheet)
SIM Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
SIM Molecular Weight
253.279 g/mol
SIM Melting Point
167 oC
SIM H2O Solubility
610 mg/L
SIM State
Solid
SIM LogP
2.447
SIM Dosage Forms
Tablet
SIM Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
SIM Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
SIM Absorption
Rapidly absorbed following oral administration.
SIM side effects and Toxicity
No information avaliable
SIM Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation.
SIM Organisms Affected
Gram negative and gram positive bacteria
