Apo-Sulfamethoxazole
Brand names,
Apo-Sulfamethoxazole
Analogs
Apo-Sulfamethoxazole
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Apo-Sulfamethoxazole
Chemical_Formula
C10H11N3O3S
Apo-Sulfamethoxazole
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Apo-Sulfamethoxazole
fda sheet
Apo-Sulfamethoxazole
msds (material safety sheet)
Apo-Sulfamethoxazole
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Apo-Sulfamethoxazole
Molecular Weight
253.279 g/mol
Apo-Sulfamethoxazole
Melting Point
167 oC
Apo-Sulfamethoxazole
H2O Solubility
610 mg/L
Apo-Sulfamethoxazole
State
Solid
Apo-Sulfamethoxazole
LogP
2.447
Apo-Sulfamethoxazole
Dosage Forms
Tablet
Apo-Sulfamethoxazole
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Apo-Sulfamethoxazole
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Apo-Sulfamethoxazole
Absorption
Rapidly absorbed following oral administration.
Apo-Sulfamethoxazole
side effects and Toxicity
No information avaliable
Apo-Sulfamethoxazole
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Apo-Sulfamethoxazole
Organisms Affected
Gram negative and gram positive bacteria