Sulfamethylisoxazole
Brand names,
Sulfamethylisoxazole
Analogs
Sulfamethylisoxazole
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Sulfamethylisoxazole
Chemical_Formula
C10H11N3O3S
Sulfamethylisoxazole
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Sulfamethylisoxazole
fda sheet
Sulfamethylisoxazole
msds (material safety sheet)
Sulfamethylisoxazole
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Sulfamethylisoxazole
Molecular Weight
253.279 g/mol
Sulfamethylisoxazole
Melting Point
167 oC
Sulfamethylisoxazole
H2O Solubility
610 mg/L
Sulfamethylisoxazole
State
Solid
Sulfamethylisoxazole
LogP
2.447
Sulfamethylisoxazole
Dosage Forms
Tablet
Sulfamethylisoxazole
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Sulfamethylisoxazole
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Sulfamethylisoxazole
Absorption
Rapidly absorbed following oral administration.
Sulfamethylisoxazole
side effects and Toxicity
No information avaliable
Sulfamethylisoxazole
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Sulfamethylisoxazole
Organisms Affected
Gram negative and gram positive bacteria