Sulphisomezole
Brand names,
Sulphisomezole
Analogs
Sulphisomezole
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Sulphisomezole
Chemical_Formula
C10H11N3O3S
Sulphisomezole
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Sulphisomezole
fda sheet
Sulphisomezole
msds (material safety sheet)
Sulphisomezole
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Sulphisomezole
Molecular Weight
253.279 g/mol
Sulphisomezole
Melting Point
167 oC
Sulphisomezole
H2O Solubility
610 mg/L
Sulphisomezole
State
Solid
Sulphisomezole
LogP
2.447
Sulphisomezole
Dosage Forms
Tablet
Sulphisomezole
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Sulphisomezole
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Sulphisomezole
Absorption
Rapidly absorbed following oral administration.
Sulphisomezole
side effects and Toxicity
No information avaliable
Sulphisomezole
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Sulphisomezole
Organisms Affected
Gram negative and gram positive bacteria