Sulfamethoxazol
Brand names,
Sulfamethoxazol
Analogs
Sulfamethoxazol
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Sulfamethoxazol
Chemical_Formula
C10H11N3O3S
Sulfamethoxazol
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Sulfamethoxazol
fda sheet
Sulfamethoxazol
msds (material safety sheet)
Sulfamethoxazol
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Sulfamethoxazol
Molecular Weight
253.279 g/mol
Sulfamethoxazol
Melting Point
167 oC
Sulfamethoxazol
H2O Solubility
610 mg/L
Sulfamethoxazol
State
Solid
Sulfamethoxazol
LogP
2.447
Sulfamethoxazol
Dosage Forms
Tablet
Sulfamethoxazol
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Sulfamethoxazol
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Sulfamethoxazol
Absorption
Rapidly absorbed following oral administration.
Sulfamethoxazol
side effects and Toxicity
No information avaliable
Sulfamethoxazol
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Sulfamethoxazol
Organisms Affected
Gram negative and gram positive bacteria