Sulphamethoxazole
Brand names,
Sulphamethoxazole
Analogs
Sulphamethoxazole
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Sulphamethoxazole
Chemical_Formula
C10H11N3O3S
Sulphamethoxazole
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Sulphamethoxazole
fda sheet
Sulphamethoxazole
msds (material safety sheet)
Sulphamethoxazole
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Sulphamethoxazole
Molecular Weight
253.279 g/mol
Sulphamethoxazole
Melting Point
167 oC
Sulphamethoxazole
H2O Solubility
610 mg/L
Sulphamethoxazole
State
Solid
Sulphamethoxazole
LogP
2.447
Sulphamethoxazole
Dosage Forms
Tablet
Sulphamethoxazole
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Sulphamethoxazole
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Sulphamethoxazole
Absorption
Rapidly absorbed following oral administration.
Sulphamethoxazole
side effects and Toxicity
No information avaliable
Sulphamethoxazole
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Sulphamethoxazole
Organisms Affected
Gram negative and gram positive bacteria