Cotrim
Cotrim Brand names, Cotrim Analogs
- Apo-Sulfamethoxazole
- Azo Gantanol
- Azo-Gantanol
- Bactrimel
- Co-trimoxazole
- Cotrim
- Cotrim D.S.
- Eusaprim
- Fectrim
- Gamazole
- Gantanol
- Gantanol-DS
- Metoxal
- Radonil
- SIM
- Septran
- Septrin
- Simsinomin
- Sinomin
- Sulfamethalazole
- Sulfamethoprim
- Sulfamethoprim-DS
- Sulfamethoxazol
- Sulfamethoxizole
- Sulfamethylisoxazole
- Sulfisomezole
- Sulmeprim
- Sulmeprim Pediatric
- Sulpha-Methoxizole
- Sulphamethalazole
- Sulphamethoxazol
- Sulphamethoxazole
- Sulphamethoxazole BP 98
- Sulphamethylisoxazole
- Sulphisomezole
- Trib
- Urobak
- Uroplus DS
- Uroplus SS
Cotrim Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Cotrim Chemical_Formula
C10H11N3O3S
Cotrim RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Cotrim fda sheet
Cotrim msds (material safety sheet)
Cotrim Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Cotrim Molecular Weight
253.279 g/mol
Cotrim Melting Point
167 oC
Cotrim H2O Solubility
610 mg/L
Cotrim State
Solid
Cotrim LogP
2.447
Cotrim Dosage Forms
Tablet
Cotrim Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Cotrim Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Cotrim Absorption
Rapidly absorbed following oral administration.
Cotrim side effects and Toxicity
No information avaliable
Cotrim Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation.
Cotrim Organisms Affected
Gram negative and gram positive bacteria
