Sulphamethoxazol
Brand names,
Sulphamethoxazol
Analogs
Sulphamethoxazol
Brand Names Mixture
- Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
- Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
- Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
- Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
- Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
- Protrin Tab (Sulfamethoxazole + Trimethoprim)
- Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
- Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
- Septra (Sulfamethoxazole + Trimethoprim)
- Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
- Septra Injection (Sulfamethoxazole + Trimethoprim)
- Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
- Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)
Sulphamethoxazol
Chemical_Formula
C10H11N3O3S
Sulphamethoxazol
RX_link
http://www.rxlist.com/cgi/generic3/gantanol.htm
Sulphamethoxazol
fda sheet
Sulphamethoxazol
msds (material safety sheet)
Sulphamethoxazol
Synthesis Reference
Kano et al., U.S. Pat. 2,888,455 (1959)
Sulphamethoxazol
Molecular Weight
253.279 g/mol
Sulphamethoxazol
Melting Point
167 oC
Sulphamethoxazol
H2O Solubility
610 mg/L
Sulphamethoxazol
State
Solid
Sulphamethoxazol
LogP
2.447
Sulphamethoxazol
Dosage Forms
Tablet
Sulphamethoxazol
Indication
For the treatment of bronchitis, prostatitis and urinary tract infections.
Sulphamethoxazol
Pharmacology
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.
Sulphamethoxazol
Absorption
Rapidly absorbed following oral administration.
Sulphamethoxazol
side effects and Toxicity
No information avaliable
Sulphamethoxazol
Patient Information
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone
formation.
Sulphamethoxazol
Organisms Affected
Gram negative and gram positive bacteria