Clodronic acid en es it fr

Clodronic acid Brand names, Clodronic acid Analogs

Clodronic acid Brand Names Mixture

  • Tenoretic (chlorthalidone + atenolol)

Clodronic acid Chemical_Formula


Clodronic acid RX_link

Clodronic acid fda sheet

Clodronic acid msds (material safety sheet)

Clodronic acid Synthesis Reference

Graf et al.; Helv. Chem.; Acta 42; 1085 (1959); U.S.Pat.3,055,904 (1962)

Clodronic acid Molecular Weight

338.767 g/mol

Clodronic acid Melting Point


Clodronic acid H2O Solubility

120 mg/L

Clodronic acid State


Clodronic acid LogP


Clodronic acid Dosage Forms


Clodronic acid Indication

For management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Clodronic acid Pharmacology

Chlorthalidone, a monosulfonamyl diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Chlorthalidone is used alone or with atenolol in the management of hypertension and edema.

Clodronic acid Absorption

Absorbed relatively rapidly after oral administration.

Clodronic acid side effects and Toxicity

Symptoms of overdose include nausea, weakness, dizziness and disturbances of electrolyte balance.

Clodronic acid Patient Information

Patients should inform their physician if they have: (1) had an allergic reaction to chlorthalidone or other diuretics or have asthma, (2) kidney disease, (3) liver disease, (4) gout, (5) systemic lupus erythematosus, or (6) been taking other drugs such as cortisone, digitalis, lithium carbonate, or drugs for diabetes.

Patients should be cautioned to contact their physician if they experience any of the following symptoms of potassium loss: excess thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate or pulse.

Patients should also be cautioned that taking alcohol can increase the chance of dizziness occurring.

Clodronic acid Organisms Affected

Humans and other mammals