Chlorphthalidone

Chlorphthalidone Brand names, Chlorphthalidone Analogs

Chlorphthalidone Brand Names Mixture

Tenoretic (chlorthalidone + atenolol)

Chlorphthalidone Chemical_Formula

C₁₄H₁₁ClN₂O₄S

Chlorphthalidone RX_link

http://www.rxlist.com/cgi/generic3/chlorthalidone.htm

Chlorphthalidone fda sheet

Chlorphthalidone msds (material safety sheet)

Chlorphthalidone Synthesis Reference

Graf et al.; Helv. Chem.; Acta 42; 1085 (1959); U.S.Pat.3,055,904 (1962)

Chlorphthalidone Molecular Weight

338.767 g/mol

Chlorphthalidone Melting Point

218-264^oC

Chlorphthalidone H₂O Solubility

120 mg/L

Chlorphthalidone State

Solid

Chlorphthalidone LogP

1.718

Chlorphthalidone Dosage Forms

Tablet

Chlorphthalidone Indication

For management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Chlorphthalidone Pharmacology

Chlorthalidone, a monosulfonamyl diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Chlorthalidone is used alone or with atenolol in the management of hypertension and edema.

Chlorphthalidone Absorption

Absorbed relatively rapidly after oral administration.

Chlorphthalidone side effects and Toxicity

Symptoms of overdose include nausea, weakness, dizziness and disturbances of electrolyte balance.

Chlorphthalidone Patient Information

Patients should inform their physician if they have: (1) had an allergic reaction to chlorthalidone or other diuretics or have asthma, (2) kidney disease, (3) liver disease, (4) gout, (5) systemic lupus erythematosus, or (6) been taking other drugs such as cortisone, digitalis, lithium carbonate, or drugs for diabetes.

Patients should be cautioned to contact their physician if they experience any of the following symptoms of potassium loss: excess thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate or pulse.

Patients should also be cautioned that taking alcohol can increase the chance of dizziness occurring.

Chlorphthalidone Organisms Affected

Humans and other mammals